--- title: "Play It Again, Brian (S06E10) | familyguy.co.uk" canonical: "https://familyguy.co.uk/episodes/s06e10-play-it-again-brian/" updatedDate: 2026-09-06 author: Alex Moss description: "Play It Again, Brian: Family Guy season 6 episode 10 (S06E10), first aired 2 March 2008. Writer and director credits." --- # Play It Again, Brian Episode 10 of Family Guy season 6 (S06E10), the 108th Family Guy episode overall. Written by Danny Smith and directed by John Holmquist. First broadcast on 2 March 2008. ## Story Peter and Lois are struggling after he repeatedly abandons her for Quagmire, Cleveland and Joe. Brian wins an award for an essay and invites the couple to Martha's Vineyard for the presentation, hoping the trip will help. With the neighbours unavailable, Herbert is hired to mind Meg, Chris and Stewie. At the hotel Peter keeps wandering off, so Lois spends her time with Brian. He reveals the essay was about her, then makes an aggressive pass, which she rejects. The next morning Peter confronts Brian at the bar and the argument becomes a fist fight. Afterwards the two agree never to let Lois divide them. Brian apologises to Lois and admits the essay was largely copied from Summer of '42. She confides that she sometimes shares his feelings but chooses to stay with Peter. ## Production and reception - Danny Smith wrote the episode, his first writing credit of the season, and John Holmquist directed his second episode of the season after "Stewie Kills Lois". ([Wikipedia: Play It Again, Brian](https://en.wikipedia.org/wiki/Play_It_Again%2C_Brian)) - Seth MacFarlane performed the two musical numbers that aired; a third, sung by Mike Henry as Herbert, was cut for time and appears on the DVD. ([Wikipedia: Play It Again, Brian](https://en.wikipedia.org/wiki/Play_It_Again%2C_Brian)) - The title refers to Woody Allen's Play It Again, Sam, and the song As Time Goes By from that film is heard, sung by MacFarlane. ([Wikipedia: Play It Again, Brian](https://en.wikipedia.org/wiki/Play_It_Again%2C_Brian)) - 20th Century Fox Home Entertainment put the episode on the Volume 7 DVD, released in the United States and Canada on 16 June 2009. ([Wikipedia: Play It Again, Brian](https://en.wikipedia.org/wiki/Play_It_Again%2C_Brian)) - Ahsan Haque of IGN rated it 7.2 out of 10 and Genevieve Koski of The A.V. Club graded it B minus, while Brad Trechak of TV Squad reviewed it favourably. ([Wikipedia: Play It Again, Brian](https://en.wikipedia.org/wiki/Play_It_Again%2C_Brian)) ## Facts | Fact | Detail | | --- | --- | | Season | 6 | | Episode | 10 of 12 | | Overall | No. 108 | | Code | S06E10 | | First aired | 2 March 2008 | | Directed by | John Holmquist | | Written by | Danny Smith | | Production code | 6ACX01 | | Source | Wikipedia: Family Guy season 6 | | Wikidata | Q4047071 | | IMDb | tt1192952 | | Verification | Checked against Wikidata and IMDb: title, date, numbering and credits agree | | US viewers | 7.80 million | ## Voices | Voice | Characters | | --- | --- | | Seth MacFarlane | Peter Griffin, Brian Griffin, Stewie Griffin | | Alex Borstein | Lois Griffin, Chemotherapy Patient's Wife | | Seth Green | Chris Griffin | | Mila Kunis | Meg Griffin | | Mike Henry | Cleveland Brown, John Herbert, Jaws | | Jessica Barth | Brandee | | Phil LaMarr | BET Announcer | | Bruce Lanoil | Nathan Lane | | Rachael MacFarlane | Audrey Hepburn | | Danny Smith | Priest | Principal voice credits as recorded by IMDb, which lists up to ten credits per episode, so recurring characters can be missing here. Guest voices below come from Wikipedia and TVmaze. ### Guest voices - Mike Henry as Herbert - Bruce Lanoil as Nathan Lane ## Links - Season: [6](https://familyguy.co.uk/episodes/season-6/) - Source: [Wikipedia: Family Guy season 6](https://en.wikipedia.org/wiki/Family_Guy_season_6) - Wikidata: [Q4047071](https://www.wikidata.org/wiki/Q4047071) - IMDb: [tt1192952](https://www.imdb.com/title/tt1192952/) - US viewers: [7.80 million](https://en.wikipedia.org/wiki/Family_Guy_season_6) ## Navigation - Previous: [S06E09 Back to the Woods](https://familyguy.co.uk/episodes/s06e09-back-to-the-woods/) - Next: [S06E11 The Former Life of Brian](https://familyguy.co.uk/episodes/s06e11-the-former-life-of-brian/) - Season hub: [Season 6](https://familyguy.co.uk/episodes/season-6/) - All episodes: [Family Guy episode guide](https://familyguy.co.uk/episodes/) ## Season 6: episode 10 of 12 - S06E01 [Blue Harvest](https://familyguy.co.uk/episodes/s06e01-blue-harvest/) - S06E02 [Movin' Out (Brian's Song)](https://familyguy.co.uk/episodes/s06e02-movin-out-brians-song/) - S06E03 [Believe It or Not, Joe's Walking on Air](https://familyguy.co.uk/episodes/s06e03-believe-it-or-not-joes-walking-on-air/) - S06E04 [Stewie Kills Lois](https://familyguy.co.uk/episodes/s06e04-stewie-kills-lois/) - S06E05 [Lois Kills Stewie](https://familyguy.co.uk/episodes/s06e05-lois-kills-stewie/) - S06E06 [Padre de Familia](https://familyguy.co.uk/episodes/s06e06-padre-de-familia/) - S06E07 [Peter's Daughter](https://familyguy.co.uk/episodes/s06e07-peters-daughter/) - S06E08 [McStroke](https://familyguy.co.uk/episodes/s06e08-mcstroke/) - S06E09 [Back to the Woods](https://familyguy.co.uk/episodes/s06e09-back-to-the-woods/) - S06E10 Play It Again, Brian (this entry) - S06E11 [The Former Life of Brian](https://familyguy.co.uk/episodes/s06e11-the-former-life-of-brian/) - S06E12 [Long John Peter](https://familyguy.co.uk/episodes/s06e12-long-john-peter/) --- Unofficial fan resource. 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