Season 17 · Episode 1 · First aired 30 September 2018
Married... with Cancer
Episode 1 of Family Guy season 17 (S17E01), the 310th Family Guy episode overall. Written by Aaron Lee and directed by Mike Kim. First broadcast on 30 September 2018.
Story
Brian falls in love with Jess Schlotz, a woman who has cancer, and decides to marry her. The wedding goes ahead. He comes to regret the choice when the pair learn that her cancer has gone into remission, leaving him with a marriage he had not expected to keep.
Production and reception
- Jess Schlotz, the woman Brian marries, is voiced by Casey Wilson. Wikipedia, Family Guy season 17
Voices
| Voice | Characters |
|---|---|
| Seth MacFarlane | Peter Griffin, Brian Griffin, Stewie Griffin |
| Alex Borstein | Lois Griffin, Helen |
| Seth Green | Chris Griffin, Driver |
| Mila Kunis | Meg Griffin, Meg Griffin |
| Mike Henry | Bruce the Performance Artist, Theater Patron |
| Sanaa Lathan | Fangirl |
| Rachael MacFarlane | Club Girl, Fangirl |
Principal voice credits as recorded by IMDb, which lists up to ten credits per episode, so recurring characters can be missing here. Guest voices below come from Wikipedia and TVmaze.
Guest voices
- Sanaa Lathan as Fangirl
- Casey Wilson as Jess
- Jay Pharoah as Kanye West
- Rachael MacFarlane as Club Girl
- Josh Robert Thompson as Dennis Franz
- John Viener as Tinazidine Man
Season 17: episode 1 of 20
- E1Married... with CancerYou are here
- E2Dead Dog Walking
- E3Pal Stewie
- E4Big Trouble in Little Quahog
- E5Regarding Carter
- E6Stand by Meg
- E7The Griffin Winter Games
- E8Con Heiress
- E9Pawtucket Pete
- E10Hefty Shades of Gray
- E11Trump Guy
- E12Bri, Robot
- E13Trans-Fat
- E14Family Guy Lite
- E15No Giggity, No Doubt
- E16You Can't Handle the Booth!
- E17Island Adventure
- E18Throw It Away
- E19Girl, Internetted
- E20Adam West High
SourceFacts from Wikipedia: Family Guy season 17 (CC BY-SA 4.0). Spotted an error? See corrections.
Provenance
Facts only- Data refreshed
- 6 September 2026
- Verification
- Checked against Wikidata and IMDb: title, date, numbering and credits agree
- Licence
- Facts are not copyrightable. Source text on Wikipedia is CC BY-SA 4.0; Wikidata is CC0; IMDb data is used for verification under its non-commercial terms.
- Note
- The story summary and notes were written for this site from the sources listed, by Claude in Claude Code on 2026-09-08, awaiting editorial review. Facts only; no dialogue is reproduced. Voice credits: Information courtesy of IMDb (https://www.imdb.com). Used with permission. Guest cast data from TVmaze (https://www.tvmaze.com), CC BY-SA.