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Season 15 · Episode 6 · First aired 13 November 2016

Hot Shots

Episode 6 of Family Guy season 15 (S15E06), the 275th Family Guy episode overall. Written by David A. Goodman and directed by John Holmquist. First broadcast on 13 November 2016.

Story

Peter and Lois become convinced that having Stewie vaccinated would leave him autistic, so they keep him from his injections and join the anti-vaccination movement. Their stance leads to an outbreak of measles in Quahog, which grows into an epidemic.

Voices

VoiceCharacters
Seth MacFarlanePeter Griffin, Brian Griffin, Stewie Griffin
Alex BorsteinLois Griffin
Seth GreenChris Griffin
Mila KunisMeg Griffin
Rachael MacFarlaneMiss Tammy

Principal voice credits as recorded by IMDb, which lists up to ten credits per episode, so recurring characters can be missing here. Guest voices below come from Wikipedia and TVmaze.

Guest voices

  • Patrick Warburton as Joe Swanson
  • Fred Tatasciore as John Goodman
  • Sean Penn as Sean Penn

Season 15: episode 6 of 20

  1. E1The Boys in the Band
  2. E2Bookie of the Year
  3. E3American Gigg-olo
  4. E4Inside Family Guy
  5. E5Chris Has Got a Date, Date, Date, Date, Date
  6. E6Hot ShotsYou are here
  7. E7High School English
  8. E8Carter and Tricia
  9. E9How the Griffin Stole Christmas
  10. E10Passenger Fatty-Seven
  11. E11Gronkowsbees
  12. E12Peter's Def Jam
  13. E13The Finer Strings
  14. E14The Dating Game
  15. E15Cop and a Half-wit
  16. E16Saturated Fat Guy
  17. E17Peter's Lost Youth
  18. E18The Peter Principal
  19. E19Dearly Deported
  20. E20A House Full of Peters

Season hub with air dates and credits for all 20 episodes

SourceFacts from Wikipedia: Family Guy season 15 (CC BY-SA 4.0). Spotted an error? See corrections.

Provenance

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6 September 2026
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Note
The story summary and notes were written for this site from the sources listed, by Claude in Claude Code on 2026-09-08, then checked against those sources in a separate review pass by Claude in Claude Code on 2026-10-06; not read by a person. Facts only; no dialogue is reproduced. Voice credits: Information courtesy of IMDb (https://www.imdb.com). Used with permission. Guest cast data from TVmaze (https://www.tvmaze.com), CC BY-SA.