Season 16 · Episode 13 · First aired 25 March 2018
V Is for Mystery
Episode 13 of Family Guy season 16 (S16E13), the 302nd Family Guy episode overall. Written by David A. Goodman and directed by Joseph Lee. First broadcast on 25 March 2018.
Story
The episode is a parody of Sherlock Holmes, with the regular cast taking the roles. Stewie appears as Holmes himself, and Brian is cast as Doctor Watson at his side. A string of murders gives the two of them a set of mysteries to work on.
Voices
| Voice | Characters |
|---|---|
| Seth MacFarlane | Peter Griffin as Professor Moriarty, Brian Griffin as Dr. John Watson, Stewie Griffin as Sherlock Holmes |
| Alex Borstein | Lois Griffin as Constance |
| Seth Green | Chris Griffin as Queen Victoria |
| Mila Kunis | Meg Griffin, Meg Griffin |
| Mike Henry | Cleveland Brown as Businessman, Bruce the Performance Artist as Chimey Sweep, Train Crossing Guard |
| Steve Callaghan | Distinguished Man #1 |
| Tom Ellis | Oscar Wilde |
| Mark Hentemann | Opie as Distinguished Passenger, Train Conductor |
| Tom Hollander | Distinguished Man #2 |
| Rachael MacFarlane | Prostitute |
Principal voice credits as recorded by IMDb, which lists up to ten credits per episode, so recurring characters can be missing here. Guest voices below come from Wikipedia and TVmaze.
Guest voices
- Mark Hentemann as Opie, Train Conductor
- Tom Ellis as Oscar Wilde
- Rachael MacFarlane as Prostitute
- Tom Hollander as Distinguished Man #2
- Steve Callaghan as Distinguished Man #1
Season 16: episode 13 of 20
- E1Emmy-Winning Episode
- E2Foxx in the Men House
- E3Nanny Goats
- E4Follow the Money
- E5Three Directors
- E6The D in Apartment 23
- E7Petey IV
- E8Crimes and Meg's Demeanor
- E9Don't Be a Dickens at Christmas
- E10Boy (Dog) Meets Girl (Dog)
- E11Dog Bites Bear
- E12Send in Stewie, Please
- E13V Is for MysteryYou are here
- E14Veteran Guy
- E15The Woof of Wall Street
- E16Family Guy Through the Years
- E17Switch the Flip
- E18HTTPete
- E19The Unkindest Cut
- E20Are You There God? It's Me, Peter
SourceFacts from Wikipedia: Family Guy season 16 (CC BY-SA 4.0). Spotted an error? See corrections.
Provenance
Facts only- Data refreshed
- 6 September 2026
- Verification
- Checked against Wikidata and IMDb: title, date, numbering and credits agree
- Licence
- Facts are not copyrightable. Source text on Wikipedia is CC BY-SA 4.0; Wikidata is CC0; IMDb data is used for verification under its non-commercial terms.
- Note
- The story summary and notes were written for this site from the sources listed, by Claude in Claude Code on 2026-09-08, awaiting editorial review. Facts only; no dialogue is reproduced. Voice credits: Information courtesy of IMDb (https://www.imdb.com). Used with permission. Guest cast data from TVmaze (https://www.tvmaze.com), CC BY-SA.